Improving lives with cutting-edge chemistry
GlycoSyn is a world-leader in carbohydrate, polymer, and complex chemistry. We can help you as a contract development and manufacturing organization (CDMO) or a contract research organization (CRO).
We’ve been passionate about creating life-changing drugs since we started 20 years ago. Our experience in current good manufacturing practice (cGMP) means we can help you take your products from concept to the lab and into the clinic.
What we do
We have a distinguished track record of guiding our clients through drug discovery and into successful regulatory submission. Our team of friendly experts can help de-risk your drug’s chemistry, manufacturing, and controls (CM&C) development programme.
Our specialised expertise, quality focus, and regulatory understanding mean your products are safe in our hands and your intellectual property is safe in our care.
Our services include:
Discovery
We’ve proven time and again that we’re steadfast in helping our clients meet their goals.
As carbohydrate and polymer experts, we thrive on tricky chemistry and engineering challenges. We enjoy channelling our creativity by painstakingly mapping out routes to the most intricate molecules.
From route selection to chemistry optimisation, from chemical to chemo-enzymatic methods, we deliver complex molecules at the high standards you need.
Development
We excel at the complex chemistry that makes novel pharmaceutical ingredients.
Our chemical process development and analytical teams are highly skilled. We can ensure safe, rapid, and cost-effective scale-up of your multi-step chemical processes. Our dedicated development scientists are adept at chemical process optimisation. We make sure our solutions are fit for purpose and set up for success.
Analytical
We know you need a thorough understanding of your product, and we use our world-class expertise and state-of-the-art analytical equipment to help with this. We want you to go into regulatory submissions with full confidence and can guide you to a successful investigational new drug application.
Our Analytical Services division provides novel assay development, impurity identification, in-process control testing, final product release testing.
We also offer full method validation to meet ICH requirements for active pharmaceutical ingredients in pre-clinical and clinical trials
GMP Manufacturing
Our bespoke cGMP manufacturing facility is where we apply our skills in complex chemistry, scale-up manufacture, and complete rigorous quality assurance. This means we can easily manufacture carbohydrates, polymers, dendrimers, and small molecules.
True quality assurance is at the heart of our culture. We are licensed to operate under PIC/S PE 009-14 (Part II) (ICH Q7 equivalent) guidelines to deliver clinical trial active pharmaceutical ingredients (APIs).
Why work with us
We turn complex chemistry into commercial success at any scale. We have transparent, high-trust partnerships with clients from NASDAQ Pharma companies to fast-growing biotech start-ups.
We provide a niche offering in the drug development cycle, synthesising complicated bioactive molecules, and developing reliable and robust processes for manufacture.
Our points of difference:
Unparalleled Expertise
We have a rich history of ground-breaking work with international partners on small-molecule enzyme inhibitors and synthetic vaccines. We are proud to be at the forefront of drug development for some of the world’s most serious diseases.
We support cGMP manufacturing by applying our exceptional expertise in R&D, synthetic route development, scale-up synthesis, and analytical method development to a range of pharmaceutical research areas.
Transparent Process
Our delivery of high-quality and fast-paced drug substance development and manufacture is second to none. We enable human proof-of-concept studies and more effective targeted treatments for some of the world’s major diseases.
While our field of work is incredibly complex, our working approach is very down-to-earth. Transparency and good communication are at the core of our relationships. We are serious about reporting to clients, giving you full oversight of your development projects all the way to manufacture.
State-of-the-art Facilities
We can take you from milligrams to kilograms. Our custom-built cGMP facilities can manufacture active pharmaceutical ingredients (APIs) by chemical synthesis at milligram all the way to multi-kilogram scale for use in pre-clinical and clinical trials.
Our niche is delivering molecules requiring intrinsically complex manufacturing requirements. We have specialist capabilities well suited to purifying carbohydrates and polymers. Our deep understanding of carbohydrate chemistry means we can easily handle cryogenic reactions and high-pressure conditions at scale.
