Improving lives with cutting-edge chemistry

GlycoSyn is a world-leader in carbohydrate, polymer, pharmaceutical excipient and complex chemistry. We can help you as a contract development and manufacturing organization (CDMO) or a contract research organization (CRO).

We’ve been passionate about creating life-changing drugs since we started 20 years ago. Our experience in current good manufacturing practice (cGMP) means we can help you take your products from concept to the lab and into the clinic.

What we do

We provide a niche offering in the drug development cycle, synthesising complicated bioactive molecules, and developing reliable and robust processes for manufacture.

This is backed by a distinguished track record of guiding our clients through drug discovery and into successful regulatory submission. Our team of friendly experts can help de-risk your drug’s chemistry, manufacturing, and controls (CM&C) development programme.

Our specialised expertise, quality focus, and regulatory understanding mean your products are safe in our hands and your intellectual property is safe in our care.

Why work with us

We turn complex chemistry into commercial success at any scale. Creating high-trust partnerships with our clients is paramount to this mission:  transparency and good communication are at the core of our relationships. 

We’re constantly looking ahead to work out how we can impact more people for the better. At GlycoSyn, our relentless mission is to use complex chemistry to help make humans healthier and to improve lives.

Our points of difference:

Discovery

We’ve proven time and again that we’re steadfast in helping our clients meet their goals.

As carbohydrate and polymer experts, we thrive on tricky chemistry and engineering challenges. We enjoy channelling our creativity by painstakingly mapping out routes to the most intricate molecules.

From route selection to chemistry optimisation, from chemical to chemo-enzymatic methods, we deliver complex molecules at the high standards you need.

Development

We excel at the complex chemistry that makes novel pharmaceutical ingredients.

Our chemical process development and analytical teams are highly skilled. We can ensure safe, rapid, and cost-effective scale-up of your multi-step chemical processes. Our dedicated development scientists are adept at chemical process optimisation. We make sure our solutions are fit for purpose and set up for success.

Analytical

We know you need a thorough understanding of your product, and we use our world-class expertise and state-of-the-art analytical equipment to help with this. We want you to go into regulatory submissions with full confidence and can guide you to a successful investigational new drug application.

Our Analytical Services division provides novel assay development, impurity identification, in-process control testing, final product release testing.

We also offer full method validation to meet ICH requirements for active pharmaceutical ingredients in pre-clinical and clinical trials

GMP Manufacturing

Our bespoke cGMP manufacturing facility is where we apply our skills in complex chemistry, scale-up manufacture, and complete rigorous quality assurance. This means we can skillfully manufacture carbohydrates, polymers, lipids, dendrimers, and high functionality excipients.

True quality assurance is at the heart of our culture. We are licensed to operate under PIC/S PE 009-14 (Part II) (ICH Q7 equivalent) guidelines to deliver clinical trial active pharmaceutical ingredients (APIs).

Unparalleled Expertise

We have a rich history of ground-breaking work with international partners on small-molecule enzyme inhibitors and synthetic vaccines. We are proud to be at the forefront of drug development for some of the world’s most serious diseases.

We support cGMP manufacturing by applying our exceptional expertise in R&D, synthetic route development, scale-up synthesis, and analytical method development to a range of pharmaceutical research areas.

Transparent Process

Our delivery of high-quality and fast-paced drug substance development and manufacture is second to none. We enable human proof-of-concept studies and more effective targeted treatments for some of the world’s major diseases.

While our field of work is incredibly complex, our working approach is very down-to-earth. Transparency and good communication are at the core of our relationships. We are serious about reporting to clients, giving you full oversight of your development projects all the way to manufacture.

State-of-the-art Facilities

We can take you from milligrams to kilograms. Our custom-built cGMP facilities can manufacture active pharmaceutical ingredients (APIs) by chemical synthesis at milligram all the way to multi-kilogram scale for use in pre-clinical and clinical trials.

Our niche is delivering molecules requiring intrinsically complex manufacturing requirements. We have specialist capabilities well suited to purifying carbohydrates and polymers. Our deep understanding of carbohydrate chemistry means we can easily handle cryogenic reactions and high-pressure conditions at scale.

Our Partners

What our clients say about us

“When GRO Biosciences was looking for a skilled partner in the synthetic carbohydrate chemistry space, we surveyed a number of firms.  Glycosyn offered us a blend of competence, creativity, and ease of interaction that keeps us coming back for more. 

What started as a single project has now grown into 5 projects across 30 months and counting.  We have dealt with a variety of team members at Glycosyn, all of whom bring strong expertise in their subject matter areas and a commitment to getting the job done.  Given the other partners that we diligenced for our projects, it simply wouldn’t be possible to do with them what we’re doing with Glycosyn.”

Christopher Gregg CSO, GRO Biosciences

“GlycoSyn not only have excellent facilities supported by world class staff but importantly from a client’s perspective, understand the pharmaceutical industry needs and demanding standards from laboratory work through to process design and scale up under GMP.

This, together with not only a “can do” but a “will do” attitude has significantly contributed to our ongoing success.”

Philip Marshall CEO, Oncology Research International Limited

“I’ve had the great fortune to work with GlycoSyn for over 10 years  on projects that span my time at Spinifex Pharmaceutical and Starpharma.

In all their work for me they have demonstrated a very high level of technical proficiency as they developed scalable synthetic routes to APIs and intermediates and executed cGMP campaigns. Their facility is first-class and is supported by an excellent analytical chemistry group and a robust quality assurance system.

What sets GlycoSyn apart is they do more than just ‘fee-for-service’ work; they commit to a project as if it were their own.”

Tom McCarthy CEO, Spinifex Pharmaceuticals